The Paterson-Kelly Syndrome

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The Paterson-kelly Syndrome.

Dysphagia localized to the post-cricoid region occurring mainly in middle-aged women was first fully described in the papers of Paterson (1919) and Kelly (1919). Kelly noted an association with anaemia, superficial glossitis, and angular stomatitis, while Paterson remarked on " the not infrequent supervention of malignant disease at the mouth of the gullet." Vinson (1922) observed the developme...

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Plummer-Vinson syndrome, PVS Paterson-Kelly syndrome Paterson-Brown Kelly syndrome Sideropenic dysphagia

Plummer-Vinson or Paterson-Kelly syndrome presents as a classical triad of dysphagia, irondeficiency anemia and esophageal webs. Exact data about epidemiology of the syndrome are not available; the syndrome is extremely rare. Most of the patients are white middle-aged women, in the fourth to seventh decade of life but the syndrome has also been described in children and adolescents. The dysphag...

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Histological Findings in the Paterson-kelly Syndrome.

Forty-one specimens taken from lesions in the post-cricoid region of patients with the Paterson-Kelly syndrome have been examined. Most webs consist of normal oesophageal mucosa which may be associated with underlying muscle and nerve lesions. Strictures also show a chronic non-specific inflammation often with epithelial changes and sometimes squamous carcinoma. Other lesions observed clinicall...

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Paterson-kelly Syndrome in Adolescence: a Report of Five Cases.

Dysphagia in the post-cricoid region is usually found in middle-aged women and may be associated with anaemia (Jacobs and Kilpatrick, 1964). Patients with this condition sometimes have a post-cricoid web which can be seen radiologically. Although cases may occasionally be seen in women below the age of 30, no cases occurring during adolescence have been reported before in the literature. The pr...

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)on Paterson and Poetic Autonomy

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ژورنال

عنوان ژورنال: BMJ

سال: 1964

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5401.79